Neuroinflammation Common in Familial Frontotemporal Dementia
Neuroinflammation appears to be a typical feature of the three most common monogenic forms of familial frontotemporal dementia (FTD), according to a new case series from the U.K.
Smoking at Night Linked to Insomnia, Shorter Sleep Times
Smoking cigarettes at night shows a stronger link to poor sleep than does smoking at earlier times in the day, according to a new study.
A Reality Check on the Costs of Menstruation
Getting caught without a pad or a tampon outside the home is par for the course many, but for women without financial resources, access to sanitary products isn’t always possible.
Two Rare Syndromes, One Patient in Rerun Hell
A combination of two unusual syndromes had one patient convinced he had seen every episode of every TV show he watched and had previously met every person he encountered. Find out how his rerun hell ended.
Taxing Pot: Risk, Reward, Revenues
With most Americans in favor of legalized marijuana, how long before recreational pot becomes available across the US?
Three Key Factors Tied to Higher Suicide Risk in BPD
Three specific symptoms may help clinicians identify patients with borderline personality disorder at highest risk for suicide.
Oh, What a Kiwi Can Do For You
Kiwifruit do not get the attention they deserve. These sweet, furry little fruits are a nutrient-dense fruit with many health benefits.
Review Shows That Pharma Payments Do Influence Prescribing
While many physicians resist the idea that pharma payments influence their prescribing, a new review finds a dose-response relationship between the two.
For Nurses Feeling the Strain of the Pandemic, Virus Resurgence Is 'Paralyzing'
COVID-19's toll weighs heavily on nurses, who can suffer stress and other psychological problems if they don't believe they are able to help their patients sufficiently.
B-cell Lymphoma Might Respond to N-myristoyltransferase Inhibition
Targeting N-myristoylation might prove to be an effective treatment for B-cell lymphoma and other cancers, according to a preclinical study.
Immediate Breast Reconstruction Feasible Following Neoadjuvant Chemo
Long-term oncologic outcomes following neoadjuvant chemotherapy for breast cancer are similar with immediate breast reconstruction and conventional mastectomy alone, regardless of response to chemo, according to a retrospective study.
Ocular Side Effects Possible With Checkpoint Inhibitors
People who use immune-checkpoint inhibitors have an increased risk of noninfectious uveitis and myasthenia gravis, according to a database study.
Age No Barrier to Weight Loss in Those With Morbid Obesity
Healthcare professionals should recognize the importance of weight loss in the over 60s and include them in programs to treat obesity, say researchers who found comparable reductions to younger people.
New Drug Approved for Neuroblastoma Based on MSKCC Research
Naxitamab has been approved for pediatric and adult patients with relapsed/refractory neuroblastoma in the bone and bone marrow that has responded to prior therapy.
Tyrosine Kinase Inhibitor Discontinuation Can Improve CML Outcomes
In patients with chronic myeloid leukemia (CML), discontinuing tyrosine kinase inhibitor (TKI) therapy is safe and associated with better patient-reported outcomes, a nonrandomized trial reveals.
New Assay Platform Enhances Detection of Circulating Breast Cancer Cells
Detection of circulating tumor cells (CTCs) in a breast cancer model was improved by a novel assay platform that uses a dual-receptor recognition and signal amplification strategy, researchers say.
Patients Cured of HCV Still at High Liver Cancer Risk
The burden of hepatocellular carcinoma (HCC) appears likely to move from patients who currently have hepatitis C virus (HCV) infection to those who have previously been cured, a new modeling study suggests.
Incidence of Stroke, But Not MI, Increasing in Young People
The incidence of stroke increased among younger adults in a retrospective study, while acute myocardial infarction, despite sharing many cardiovascular risk factors with stroke, did not change.
Biomarker May Flag Response to Novel AF Intervention
Neuromodulation of the tragus nerve using a TENS-type device has been shown to reduce AF burden. A biomarker, neuropeptide Y, may flag who will or won't respond to this intervention.
Older Adults More Resilient to COVID's Mental Health Impact
Older adults, as a group, appear to be withstanding the mental health strains of the COVID-19 pandemic better than all other age groups.
High Systolic BP After EVT for Stroke Tied to Poor Outcomes
Greater disability and increased risk of symptomatic intracranial hemorrhage are more likely if a patient has high blood pressure during the first 6 hours after undergoing endovascular therapy.
Parents Complain That Pediatricians, Wary of COVID, Shift Sick Kids to Urgent Care
Referrals of children to urgent care clinics or the ER have become so prevalent that the AAP came out with interim guidance on how practices can safely continue to see patients.
New Study Pinpoints How Mediterranean Diet Reduces Diabetes Risk
A 20-year follow-up of participants in the Women's Health Study unveils some of the mechanisms by which the Mediterranean diet is believed to reduce the risk of type 2 diabetes.
Approval of COVID-19 Vaccines Will Change Nature of Clinical Trials
Infectious disease experts agreed with ethicists that placebo-controlled trials would no longer be ethical, but said there are valid alternatives.
Need a COVID-19 Nurse? That'll Be $8,000 a Week
Early in the pandemic, hospitals were competing for ventilators, COVID tests, and personal protective equipment. Now, sites across the country are competing for nurses.
Higher Dose 'Z-Drugs' Tied to Serious Risks in Dementia Patients
Dementia patients prescribed higher doses of "Z-drugs" for sleep disturbances face an increased risk for fractures, falls, and strokes, a new study shows.
More Children Swallowed Powerful Magnets After Federal Ban Blocked
After a federal rule banning powerful rare-earth magnets was blocked by a judge, increasing numbers of children have been turning up in U.S. emergency rooms having swallowed the tiny objects, a new study finds.
When and Why Do Diverticulitis Patients Need Surgery?
An update to the American Society of Colon and Rectal Surgeons (ASCRS) guideline on diverticular disease suggests that surgery may not be needed in many cases, while a study of laparoscopic resection shows that quality of life may improve, although risks
Absolute Measures of Efficacy, Harms Still Missing From Most Clinical Trial Reports
Absolute measures of efficacy and harms are usually missing from reports of clinical trials in high-impact medical journals, flying in the face of long-standing guideline recommendations, researchers have found.
Children With Exercise-Induced Respiratory Symptoms May Get Conflicting Diagnoses
Children referred to outpatient clinics for exercise-induced respiratory symptoms often get a diagnosis that differs from the one they received from their primary care provider, a Swiss study suggests.
Plasma From Recovered Patients Shows Little Benefit in Those Hospitalized With COVID-19: Study
Using blood plasma from COVID-19 survivors to treat patients with severe pneumonia caused by the novel coronavirus showed little benefit, according to data released on Tuesday from a clinical trial in Argentina.
CMS' Final Rule on Stark Law Is Mixed Bag, Observers Say
While a new exception will help physicians coordinate care in value-based arrangements, existing waivers and continued restrictions undercut the rule's goal.
Hospitals in the Midwest Strapped for Beds, Staff
With the number of COVID-19 inpatients tripling in the past 2 weeks alone, staff at the University of Iowa Hospitals and Clinics say they feel like they've been called to war.
Patient Health Suffers Amid Pandemic Healthcare Shortages
Delayed healthcare brought on by the pandemic is taking its toll on patients, according to a recent survey of primary care doctors.
HHS Alters Plan for Vaccine Distribution
Distribution plans for the Covid-19 vaccine have shifted; many groups considered at-risk, once first in line to get the vaccine, now will have to wait.
Resuscitation More Likely With Faster Time to Head-Up CPR
A preliminary study employed a "package" consisting of a head-up positioning device and different devices for CPR, so "it's hard to know which component is most important," said one expert.
Medical Leaders Launch Grassroots Doctors' Alliance
Inaugural town hall introduces a movement to unite doctors behind a single issue: the restoration of the physician–patient relationship.
Study Casts Doubt on Plasma as COVID Treatment
Early in the COVID-19 pandemic, anecdotal reports suggested that infusing very sick patients with the blood plasma of people who'd survived the disease might help boost outcomes. But new study findings, along with disappointing results from prior trials,
Leaders Urge Caution as COVID Surges in Nursing Homes
Coronavirus cases in the nation’s 15,600 nursing homes have reached a record high, leaving operators struggling to protect staff and residents.
Doctors Without Borders to Withdraw From Venezuela Hospital Due to Restrictions
Medecins Sans Frontieres will withdraw from a collaboration with a Venezuelan hospital to treat COVID-19 patients due to restrictions on specialists' ability to enter the country, the medical NGO said on Tuesday.
New Legal Push Aims to Speed Magic Mushrooms to Dying Patients
A proposal in Washington state would use right-to-try laws to allow terminally ill patients access to psilocybin — the famed magic mushrooms of America's psychedelic '60s — to ease depression and anxiety.
NHS Thumbs Up to CGM for Pregnant Type 1 Diabetes Patients
As CGM is made available for type 1 diabetes pregnancies in the UK, an audit has underscored the association between raised A1c levels and poor outcomes in all pregnant patients with diabetes.
Some Advice from the Online Dating-Tested
For those frustrated with online dating, a new rules of engagement plan could be in order.
Rural Areas Send Their Sickest Patients to Cities
Critically ill rural patients are often sent to city hospitals for high-level treatment, and as their numbers grow, some urban hospitals are buckling under the added strain.
New to The Thanksgiving Menu: Cutting Yourself Slack
Instead of focusing on being “good” this holiday season, experts say focus on your needs.
Experts: COVID Vaccine May Cause Side Effects
Americans who get a shot shouldn't be surprised if they feel under the weather for a few days afterwards, expert say. Vaccines work to fight disease by producing an immune response within the body. And sometimes that means flu-like symptoms, such as ache
Circulating miRNA for Early Diagnosis of Multiple Myeloma
Circulating microRNAs (miRNAs) could be a potential noninvasive biomarker for early diagnosis of multiple myeloma, according to the results of a meta-analysis.
Pigment Traits, Sun Sensitivity Tied to Risk for Blood Cancers
Risk factors for keratinocyte carcinomas were associated with the risk of developing non-Hodgkin lymphomas and chronic lymphocytic leukemia in an analysis of 92,097 women.
Sedentary Postmenopausal Women Have Higher HF Risk
The more time older women spent sitting or lying down, the more likely their risk for hospitalization for heart failure.
Xofluza Can Now Be Used for Postexposure Flu Prophylaxis
The antiviral baloxavir marboxil, previously available only in tablet form, is also now available as granules for mixing in water.
CDC Panel Delves Into Priorities for COVID Vaccine Distribution
The CDC's ACIP panel saw a need to get early doses of COVID-19 vaccines to hospital support staff. They also debated whether nursing home residents should be in the first wave of vaccinations.
A Reality Check on COVID-19 Risks From Air Travel
While airlines promote holiday deals and encourage travel, a nationwide COVID-19 surge makes getting on a plane risky.
North Dakota Nurses Fight Policy Asking Infected HCWs to Stay on Job
In a highly controversial move, the North Dakota governor has said that symptomatic healthcare workers who are positive for COVID-19 can continue working, much to the dismay of the nursing community.
These Frontline Workers Could Have Retired
An investigation by KHN and The Guardian shows that 329 health care workers age 65 or older have reportedly died of COVID-19.
Ra Remission? Stop Methotrexate, Keep Etanercept
In patients with RA whose disease is well controlled by methotrexate and etanercept, withdrawal of methotrexate led to long-term outcomes that were nearly as good as continuation of combination therapy.
ECG Increases AF Detection, but Not Anticoagulation, After Stroke
Researchers suggest that additional ECG monitoring should be focused on patients with stroke who are at increased risk of atrial fibrillation.
Is Heart Failure Reversible? New Study Says, “Maybe”
University of Utah Health researchers say heart failure could be reversed with a new treatment.
Rhinitis Options: Fast Relief or Delayed Long-term Effect
An oral antihistamine improved nasal airflow quickly in ragweed-allergic patients, but effects faded fast, whereas a nasal spray provided no immediate relief in a head-to-head comparison.
Dealing with Diabetes
HHS Shipping 30K Doses of Regeneron COVID Monoclonal Antibody Today
Federal officials say they do not anticipate shortages and are hoping to ignite interest in monoclonal therapy.
COVID Cases Could Top 20 Million in January, Model Shows
Depending on how well people adhere to proper precautions, a new forecast model predicts the US could nearly double its number of cases from the current 12.4 million.
Tips on Living With Migraine
Three people share their experiences with the chronic condition and what they've learned about finding treatments that really help.
USPSTF Continues to Back Behavioral Intervention to Cut CVD Risk
Adults with risk factors for cardiovascular should be offered or referred for behavioral counseling to promote a healthy diet and physical activity, the task force recommends.
Hundreds of Bodies Remain in Mobile Morgues in New York City
While some are unclaimed bodies, many of the deceased have families who still can't afford to pay for the burial, or the families couldn't be reached.
Anxiety Might Speed Alzheimer's: Study
Older adults with memory problems may progress to Alzheimer's more quickly if they are also suffering from anxiety symptoms, a preliminary study suggests.
Could the Pill Reduce Asthma Attacks?
Women with asthma may suffer fewer severe symptom attacks if they are on birth control pills, a large new study suggests.
Mediterranean Diet Cuts Women's Odds for Diabetes
Overweight women who eat a Mediterranean-like diet may reduce their odds of developing type 2 diabetes by 30%, compared with women who don't, a new study suggests.
Stay on Point, Says Dr. Fauci: Help Is Coming
With three drug companies on the verge of a breakthrough vaccine against Covid-19, vaccinations could begin by the end of December.
'Dramatic' Inflammation Reduction After OHCA With Tocilizumab
A pilot study showed reduced systemic inflammatory response and cardiac injury in out-of-hospital cardiac arrest patients, with the hope of affecting mortality and neurologic outcome in larger trials.
Finerenone's Heart Benefits Hold in T2D Without CVD: FIDELIO-DKD
The nonsteroidal mineralocorticoid receptor antagonist showed cardiovascular benefits in patients with type 2 diabetes and chronic kidney disease, with or without CVD, a phase 3 trial shows.
Test for Deadly Brain Cancer Can Guide Crucial Decisions
Researchers at Johns Hopkins University have developed a new test to detect glioblastoma.
FDA Clears First Drug to Treat Ultra-Rare Metabolic Disorder
Lumasiran (Oxlumo) is the first treatment for primary hyperoxaluria type 1 (PH1), a rare genetic disorder that causes recurrent kidney stones and loss of kidney function.
'Healing' Stent on Par With Durable Polymer Stents: PIONEER III
The trial's noninferiority margin, however, raised eyebrows and calls for longer, more convincing results to be collected over 5 years of follow-up.
Amyloid in the Retina Correlates With Alzheimer's Brain Changes
Researchers have identified amyloid in the retina of living patients with cognitive decline and correlated this with brain changes.
A Call to Make Four Telehealth Provisions Permanent
Lawmakers, physicians, and advocates alike have hailed a relaxation of telehealth rules under the COVID-19 emergency declaration, and they'd like things to stay this way.
Telepsychiatry Poised to Thrive After the Pandemic
Mental health experts expect virtual and in-person visits to merge to become a standard model of care in clinical psychiatry.
New Drug Looks Good for Rare Genetic Severe Obesity
'The impact of setmelanotide in the obesity clinic is likely to mean...an increase in genetic screening to identify a subset of patients that can benefit,' said an expert.
Laughing is good for your mind and your body – here’s what the research shows
Amusement and pleasant surprises – and the laughter they can trigger – add texture to the fabric of daily life.
Immunotherapy Could Fill Unmet Need in Leptomeningeal Metastases
Immunotherapy with pembrolizumab holds promise for improving the generally dismal outlook in patients with leptomeningeal metastases, a phase 2 trial suggests.
Decades of Work, and Half a Dose of Fortune, Drove Oxford Vaccine Success
It took Oxford University's brightest minds decades of work to give them the expertise to develop a COVID-19 vaccine. In the end, it was a momentary error and a dose of good fortune that carried them over the line.
Potential New Option: 1-Month DAPT Post DES, Then Aspirin Alone
One month of dual-antiplatelet therapy followed by aspirin monotherapy in patients who've received a drug-eluting stent proved noninferior to 6-12 months of DAPT in a large trial.
In Online Dating Sea, Lots of Bait, Few Nibbles
Like so many single people these days, Jon H. entrusted his quest for love to online dating sites and apps. First there was Tinder, followed by inefficacious sojourns on Bumble, Plenty of Fish and OKCupid. So many years of swiping right. So many unrequit
Liquid Oxygen Recommended for Mobile Patients With Lung Disease
A new guideline pushes for a change to reimbursements for portable oxygen systems.
Immunodeficiency Strongly Linked to Mental Illness, Suicidality
Results of new study point to a link between antibody dysfunction and psychiatric disorders, including suicidal behavior.
Junk Food, Alcohol Often Star in Hit Movies
If there was an Oscar for "most unhealthy food in a leading role," many of America's most popular movies would be serious contenders.
IDSA Updates COVID Guidelines for Antibodies, Antivirals, Others
Infectious disease experts critically review evidence for use of bamlanivimab, address new data on remdesivir and tocilizumab, and comment on new findings for the Oxford University COVID-19 vaccine.
Vegan Diets Tied to Higher Bone Fracture Risk
Vegans face a 43% higher risk for bone fractures than meat eaters, a large British study warns. The researchers also identified a notably higher risk for hip fractures among those who eat fish but no meat (pescatarians), and among vegetarians who swear o
1 in 3 Parents Say Holiday Gathering Worth COVID Risk
In a new nationwide poll of 1,443 parents, about one in three said the benefits of gathering with families for the holidays outweighed the risk of spreading the virus.
Chili Pepper Consumption Linked to Better Midlife Survival
In a meta-analysis of four geographically diverse observational studies, a higher intake of any type of chili pepper was associated with a lower rate of death from CV disease, cancer, or all causes.
Combo DAA May Benefit Patients With Resistant HCV Genotype 3
A meta-analysis of 34 research reports found that direct-acting antiviral (DAA) combo treatment can be effective in achieving sustained virologic response in patients with HCV genotype 3.
Young Americans Lonely, Depressed During Pandemic
Loneliness, anxiety, depression and substance use have increased sharply among young American adults during the COVID-19 pandemic, a survey shows.
Many Patients With Type 2 MI Don't Get Cardiologist Evaluation
They are also less likely to get tests, recommended discharge meds, and postdischarge cardiology follow-up than those not evaluated by a cardiologist, an analysis suggests.
Even 'Safe' Levels of Air Pollution Tied to Brain Shrinkage
Even "safe" levels of air pollution may contribute to brain shrinkage and subsequent development of Alzheimer's disease.
Ready for a Covid-Impacted Holiday Season?
Coronavirus cases are spiking across the country, and local and state governments are trying to curb the spread.
Superior Cognitive Benefits With TAVR vs SAVR
Previous research has shown that high-risk patients with cognitive decline have experienced cognitive improvement after TAVR. Now, a new study suggests similar improvements in low-risk patients.
'Hidden' Prostate Cancer Usually Means Good Outcome
Negative biopsies among early-stage prostate cancer patients who've chosen active surveillance are associated with a low risk of disease progression, but they aren't a sign that their cancer has completely vanished, a new study indicates.
COVID-19 Vaccination Could Start December 11
Pfizer's coronavirus vaccine could be approved and roll out across the U.S. at the end of the second week in December, Moncef Slaoui, the chief science adviser for Operation Warp Speed, said.
New Findings on 'Exceptional Responders' to Cancer Therapies
Why do a small percentage of patients with cancer show exceptional responses to cancer therapy? The answer may lie in their genetic makeup.
The Curious Case of Three Fingers and Four iPhones
The cause of a patient's severe hand dystonia affecting three fingers had physicians stumped, but tenacious clinical investigation eventually led them to make the call on this very unusual case.
A Radiologist Who's Leaving His Mark
Salah Qanadli comes to mind when talking about modern-day radiologists.
source : webmd, medicaldaily, medscape